Serum Cholesterol and Cognitive Performance in the Framingham Heart Study

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Serum cholesterol and cognitive performance in the Framingham Heart Study.

OBJECTIVE The objective of this study was to examine the relationship between total cholesterol (TC) and cognitive performance within the context of the Framingham Heart Study, a large, community-based, prospective investigation of cardiovascular risk factors. METHODS Participants were 789 men and 1105 women from the Framingham Heart Study original cohort who were free of dementia and stroke ...

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Alcohol consumption and cognitive performance in the Framingham Heart Study.

Recent studies have indicated that moderate alcohol intake may be beneficial to cognitive functioning in women, although not necessarily in men. Data from the Framingham Heart Study, a large, prospective study of cardiovascular disease in Framingham, Massachusetts, were used to examine the relation between alcohol consumption and cognitive ability. The major research question was whether a diff...

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Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham study.

Risk of coronary heart disease over 14 years was examined prospectively in 2,282 men and 2,845 women according to their antecedent cholesterol and lipoprotein status. An increased risk proportional to antecedent serum cholesterol was found whether or not it was associated with elevated S,20 400 prebeta lipoprotein. When adjustment was made for the concomitant prebeta lipoprotein concentration a...

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High density lipoprotein cholesterol and mortality. The Framingham Heart Study.

In 12 years of follow-up for 2748 Framingham Heart Study participants ages 50 to 79, low levels of high density lipoprotein cholesterol (HDL-C) were associated with increased mortality. For men, the relative risk of death in the first HDL-C quintile (less than 35 mg/dl) as compared to the top quintile (greater than 54 mg/dl) was 1.9 for all causes, and 3.6 and 4.1 for death due to cardiovascula...

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APOE and mild cognitive impairment: the Framingham Heart Study.

BACKGROUND The risk apolipoprotein E-4 (APOE4) poses for mild cognitive impairment (MCI) may vary based on the neuropsychological definition of MCI. SETTING A community-based cohort study. METHODS Using two psychometric neuropsychological impairment definitions, we examined APOE4 and prevalent MCI among older adults or pre-MCI among middle-aged adults. Neuropsychological, clinical and genet...

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ژورنال

عنوان ژورنال: Psychosomatic Medicine

سال: 2005

ISSN: 0033-3174

DOI: 10.1097/01.psy.0000151745.67285.c2